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16-night panama canal cruise

$2,605

Royal Caribbean – Radiance of the Seas

4.4 (107)

5 Star

63%

4 Star

24%

3 Star

2 Star

1 Star

Date:

Oct 04, 2025

Ports:

San Diego → Cabo San Lucas → Mazatlan → Puerto Quetzal → Puerto Caldera (Puntarenas) → Colon → Cartagena → Grand Cayman → Fort Lauderdale

Departs Oct 04, 2025 from San Diego, California

Up to 2 deals including an Avoya Exclusive

Inside From

$2,605

Top Picks Rank: 7

13-night panama canal cruise

$1,589

Royal Caribbean – Serenade of the Seas

4.5 (214)

5 Star

64%

4 Star

27%

3 Star

2 Star

1 Star

Date:

Sep 19, 2025

Ports:

San Diego → Puerto Vallarta → Huatulco → Puerto Caldera (Puntarenas) → Cartagena → Miami

Departs Sep 19, 2025 from San Diego, California

Up to 1 deal

Inside From

$1,589

Top Picks Rank: 6

10-night panama canal cruise

$1,245

Royal Caribbean – Serenade of the Seas

4.5 (214)

5 Star

64%

4 Star

27%

3 Star

2 Star

1 Star

Date:

Apr 25, 2026

Ports:

Colon → Puerto Caldera (Puntarenas) → Huatulco → Puerto Vallarta → Los Angeles

Departs Apr 25, 2026 from Colon, Panama

Up to 2 deals

Inside From

$1,245

Top Picks Rank: 6

16-night panama canal cruise

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Royal Caribbean – Serenade of the Seas

4.5 (214)

5 Star

64%

4 Star

27%

3 Star

2 Star

1 Star

Date:

Apr 13, 2025

Ports:

Fort Lauderdale → Grand Cayman → Cartagena → Colon → Puerto Quetzal → Puerto Vallarta → Cabo San Lucas → Los Angeles

Departs Apr 13, 2025 from Fort Lauderdale, Florida

Up to 3 deals including an Avoya Exclusive

Balcony From

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Top Picks Rank: 8

15-night panama canal cruise

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Royal Caribbean – Radiance of the Seas

4.4 (107)

5 Star

63%

4 Star

24%

3 Star

2 Star

1 Star

Date:

Apr 19, 2025

Ports:

Tampa → Grand Cayman → Cartagena → Colon → Puerto Quetzal → Puerto Vallarta → Los Angeles

Departs Apr 19, 2025 from Tampa, Florida

Up to 3 deals including an Avoya Exclusive

Balcony From

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Top Picks Rank: 7

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