Menu
Call
No Avoya Fees on Cruises or Tours. Click Here!

MSC Cruises to Africa

MSC Cruises Africa cruises are diverse and exciting, exploring everything from ancient pyramids in Egypt to guided safaris in natural reserves. Onboard the MSC Sinfonia, which sails all of MSC Cruise line’s African Cruises, guests will enjoy distinct Italian style, comfortable accommodations, countless activities, and more. In addition, on all MSC Cruises to Africa, kids sail free!

Showing 51-75 of 158 results
Roundtrip
6-Night Africa Cruise
$812
33% Off List
MSC Cruises – MSC Opera
5 Reviews
Departs Feb 28, 2025 from Funchal, Madeira Islands, Portugal
Up to 3 deals
Roundtrip
7-Night Africa Cruise
$876
33% Off List
MSC Cruises – MSC Opera
5 Reviews
Departs Mar 02, 2025 from Santa Cruz de Tenerife, Spain
Up to 3 deals
Roundtrip
4-Night Africa Cruise
$439
44% Off List
MSC Cruises – MSC Musica
4 Reviews
Departs Mar 03, 2025 from Durban, South Africa
Up to 3 deals
Roundtrip
7-Night Africa Cruise
$1,471
44% Off List
MSC Cruises – MSC Opera
5 Reviews
Departs Mar 06, 2025 from Funchal, Madeira Islands, Portugal
Up to 3 deals
3-Night Africa Cruise
$314
43% Off List
MSC Cruises – MSC Musica
4 Reviews
Departs Mar 09, 2025 from Durban, South Africa
Up to 3 deals
Roundtrip
7-Night Africa Cruise
$696
26% Off List
MSC Cruises – MSC Opera
5 Reviews
Departs Mar 09, 2025 from Santa Cruz de Tenerife, Spain
Up to 3 deals
Roundtrip
7-Night Africa Cruise
$917
38% Off List
MSC Cruises – MSC Opera
5 Reviews
Departs Mar 10, 2025 from Las Palmas, Spain
Up to 3 deals
Roundtrip
4-Night Africa Cruise
$629
46% Off List
MSC Cruises – MSC Musica
4 Reviews
Departs Mar 12, 2025 from Cape Town, South Africa
Up to 2 deals
Roundtrip
7-Night Africa Cruise
$1,411
43% Off List
MSC Cruises – MSC Opera
5 Reviews
Departs Mar 13, 2025 from Funchal, Madeira Islands, Portugal
Up to 2 deals
Roundtrip
7-Night Africa Cruise
$759
30% Off List
MSC Cruises – MSC Opera
5 Reviews
Departs Mar 16, 2025 from Santa Cruz de Tenerife, Spain
Up to 3 deals
17-Night Africa Cruise
$1,988
30% Off List
MSC Cruises – MSC Opera
5 Reviews
Departs Mar 17, 2025 from Las Palmas, Spain
Up to 3 deals
14-Night Africa Cruise
$1,641
30% Off List
MSC Cruises – MSC Opera
5 Reviews
Departs Mar 20, 2025 from Funchal, Madeira Islands, Portugal
Up to 3 deals
7-Night Africa Cruise
$1,891
46% Off List
MSC Cruises – MSC Opera
5 Reviews
Departs Mar 20, 2025 from Funchal, Madeira Islands, Portugal
Up to 3 deals
6-Night Africa Cruise
$519
MSC Cruises – MSC Opera
5 Reviews
Departs Mar 23, 2025 from Santa Cruz de Tenerife, Spain
11-Night Africa Cruise
$1,073
24% Off List
MSC Cruises – MSC Opera
5 Reviews
Departs Mar 23, 2025 from Santa Cruz de Tenerife, Spain
Up to 3 deals
9-Night Africa Cruise
$1,104
29% Off List
MSC Cruises – MSC Opera
5 Reviews
Departs Mar 23, 2025 from Santa Cruz de Tenerife, Spain
Up to 3 deals
7-Night Africa Cruise
$877
39% Off List
MSC Cruises – MSC Opera
5 Reviews
Departs Mar 27, 2025 from Valencia, Spain
Up to 3 deals
5-Night Africa Cruise
$459
MSC Cruises – MSC Opera
5 Reviews
Departs Mar 29, 2025 from Rome (Civitavecchia), Italy
14-Night Africa Cruise
$1,181
MSC Cruises – MSC Musica
4 Reviews
Departs Nov 02, 2025 from Genoa, Italy
Up to 2 deals
Roundtrip
7-Night Africa Cruise
$623
MSC Cruises – MSC Musica
4 Reviews
Departs Nov 14, 2025 from Las Palmas, Spain
Up to 2 deals
Roundtrip
7-Night Africa Cruise
$624
MSC Cruises – MSC Musica
4 Reviews
Departs Nov 16, 2025 from Santa Cruz de Tenerife, Spain
Up to 2 deals
Roundtrip
7-Night Africa Cruise
$623
MSC Cruises – MSC Musica
4 Reviews
Departs Nov 21, 2025 from Las Palmas, Spain
Up to 2 deals
Roundtrip
7-Night Africa Cruise
$638
MSC Cruises – MSC Musica
4 Reviews
Departs Nov 22, 2025 from Funchal, Madeira Islands, Portugal
Up to 2 deals
Roundtrip
7-Night Africa Cruise
$624
MSC Cruises – MSC Musica
4 Reviews
Departs Nov 23, 2025 from Santa Cruz de Tenerife, Spain
Up to 2 deals
Roundtrip
3-Night Africa Cruise
$319
MSC Cruises – MSC Opera
5 Reviews
Departs Nov 28, 2025 from Durban, South Africa
Up to 1 deal
Don't Miss the Latest Deals!
Talk to a Vacation Planner
Avoya Travel Logo Mark
Why Choose Avoya?
U.S. / Canada: 1-888-877-7042
UK: 0-800-098-8475
Australia: 1-800-651-320
International: 001-760-305-5070
Avoya Travel®
CST: 2085569-40
Fla. Seller of Travel Ref. No. ST36781
© Avoya Travel®. All Rights Reserved.
Avoya Travel Logo
Call